The second season of Spy x Family continues the adaptation of Tatsuya Endo's manga, picking up after the events of the first season. Key arcs include the Great Cruise Adventure, where Yor takes on a secret bodyguard mission aboard a luxury liner, unaware that Loid and Anya are also on board for a vacation. This leads to intense action for Yor as she protects her clients from assassins, while Loid tries to enjoy downtime and Anya uses her telepathy to navigate the chaos (and try to help). Other episodes delve deeper into the daily lives of the Forgers, Anya's struggles at Eden Academy (including her attempts to befriend Damian Desmond), Loid's ongoing efforts for Operation Strix, and the introduction of new characters who further complicate their secret lives.